9:30 AM EST
Jets at Dolphins in London: The Dolphins are on the verge of collapse and a win by New York will bury their coaching staff and, as a result, their season. The Jets are 2.5 point favorites. I think the Dolphins rally around to win this game 24-20.
1:00 PM EST
Jaguars at Colts: Quarterback Andrew Luck isn't expected to play. Can the Jaguars win in Indianapolis? Indy is the 3.5 point favorite. Look for Indianapolis to win an ugly game with Matt Hasselbeck at quarterback, 28-27.
Giants at Bills: Buffalo stands as a 5.5 point favorite over the Giants, and for good reason. The Giants have allowed the most passing yards on the season, but the Bills will be without running back LeSean McCoy. Look for the Bills to win 30-17.
Panthers at Buccaneers: The Panthers are 3.0 road favorites and I think they are going to win by more. Carolina, 27-17.
Eagles at Washington: Philadelphia needs to right the ship and Washington scares no one. Divisional games are fun and the Eagles are 3.0 point favorites. Eagles win 24-13.
Raiders at Bears: Oakland is the 3.5 point favorite and I'm loving this match-up. Derek Carr and Amari Cooper are going to have an awesome week. Raiders win 24-21.
Texans at Falcons: The Falcons are a 5.0 point favorite and Julio Jones is the most unstoppable wide receiver in football. Atlanta is underrated and should win this one big, 34-17.
Chiefs at Bengals: Are the 3.5 point favorite Bengals real? We might find out. I trust Alex Smith less than I trust Andy Dalton and both teams have great defenses. Cincinnati wins an ugly one 25-21.
4:05 PM EST
Browns at Chargers: San Diego is the 6.5 point favorite, but are coming off back-to-back losses to the Bengals and the Vikings after opening the year with a win against the Lions. The Browns are 1-2 with losses to the Jets and Raiders, and a win against the Titans. I think this is closer than expected, but the Chargers still win 21-17.
4:25 PM EST
Packers at 49ers: Green Bay will win, but the question is by how much? How are the Packers only 7.0 point favorites, and the line has tightened after opening as 9.5 point favorites. Is Green Bay going to rest Aaron Rodgers after the first quarter? Packers win 35-10.
Rams at Cardinals: The Rams have a great defensive line and they always challenge the best teams in the NFC West. Arizona is the 7.0 point favorite, but I think St. Louis covers at the end, with the Cardinals winning 24-20.
Vikings at Broncos: Denver is the 7.0 point favorite. Can the offense find its groove? The Broncos win another ugly one 23-17.
8:30 PM EST
Cowboys at Saints: Drew Brees might play for the 3.0 point favorite Saints. If so, the Saints win in a shoot out, 35-31.