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NFL Week 13 odds: Patriots open as 3-point underdogs against Bills

Related: AFC East Report: Bills cornerback Tre’Davious White out for the season with torn ACL

New England Patriots v Buffalo Bills Photo by Bryan M. Bennett/Getty Images

Coming off their sixth straight win — a 36-13 victory over Tennessee — the New England Patriots need to turn the page quickly. After all, a pivotal Week 13 road matchup against the Buffalo Bills awaits: the Patriots will travel to Western New York and fight for the AFC East lead on Monday Night Football.

While New England enters the contest at 8-4 and in the current top spot in their division, Buffalo is 7-4 and could retake the lead with a victory. Needless to say that the high-stakes battle will be one of the biggest games of the week — and arguably the Patriots’ most important game since Tom Brady’s departure following the 2019 season.

The contest projects to be a close one, and the oddsmakers agree. According to DraftKings Sportsbook, the Patriots are listed as 3-point underdogs with the over/under set at 45. Given that home field advantage is usually worth three points one can see how tight the game is expected to be.

NFL Week 13 spreads

Dallas Cowboys at New Orleans Saints

New York Giants at Miami Dolphins

Indianapolis Colts at Houston Texans

Minnesota Vikings at Detroit Lions

Philadelphia Eagles at New York Jets

Arizona Cardinals at Chicago Bears

Tampa Bay Buccaneers at Atlanta Falcons

Jacksonville Jaguars at Los Angeles Rams

Baltimore Ravens at Pittsburgh Steelers

San Francisco 49ers at Seattle Seahawks

Denver Broncos at Kansas City Chiefs